PER-6-BROMO-PER-2,3-DIMETHYL-BETA-CYCLODEXTRIN

被引：15

作者：

ALKER, D

ASHTON, PR

HARDING, VD

KONIGER, R

STODDART, JF

WHITE, AJP

WILLIAMS, DJ

机构：

[1] PFIZER LTD,CENT RES,SANDWICH CT13 9NJ,KENT,ENGLAND

[2] UNIV BIRMINGHAM,SCH CHEM,BIRMINGHAM B15 2TT,W MIDLANDS,ENGLAND

[3] UNIV LONDON IMPERIAL COLL SCI & TECHNOL,DEPT CHEM,LONDON SW7 2AY,ENGLAND

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 48期

关键词：

D O I：

10.1016/0040-4039(94)88436-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of the title compound, per-6-bromo-per-2,3-dimethyl-beta-cyclodextrin, is described, giving access to a highly soluble cyclodextrin, which may be used for further chemical modification of beta-cyclodextrin. Crystals of the target compound were grown and the solid state structure was determined by X-ray crystallography, revealing a cyclodextrin derivative whose conformation deviates substantially from C-7 symmetry.

引用

收藏

页码：9091 / 9094

页数：4

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