PILOCARPINE PRODRUGS .1. SYNTHESIS, PHYSICOCHEMICAL PROPERTIES AND KINETICS OF LACTONIZATION OF PILOCARPIC ACID-ESTERS

被引：48

作者：

BUNDGAARD, H ^{[1
]}

FALCH, E ^{[1
]}

LARSEN, C ^{[1
]}

MIKKELSON, TJ ^{[1
]}

机构：

[1] UNIV KANSAS,SCH PHARM,DEPT PHARMACEUT CHEM,LAWRENCE,KS 66045

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1986年 / 75卷 / 01期

关键词：

D O I：

10.1002/jps.2600750109

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：36 / 43

页数：8

共 41 条

[11] HYDROLYSIS AND EPIMERIZATION KINETICS OF PILOCARPINE IN BASIC AQUEOUS-SOLUTION AS DETERMINED BY HPLC
BUNDGAARD, H
HANSEN, SH
[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1982, 10 (04) : 281 - 289
[12] PRO-DRUGS AS DRUG DELIVERY SYSTEMS .17. ESTERS OF 4-HYDROXYBUTYRIC ACIDS AS POTENTIAL PRO-DRUG TYPES FOR GAMMA-LACTONES
BUNDGAARD, H
LARSEN, C
[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1980, 7 (02) : 169 - 176
[13] PILOCARPIC ACID-ESTERS AS NOVEL SEQUENTIALLY LABILE PILOCARPINE PRODRUGS FOR IMPROVED OCULAR DELIVERY
BUNDGAARD, H
FALCH, E
LARSEN, C
MOSHER, GL
MIKKELSON, TJ
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (08) : 979 - 981
[14] BUNDGAARD H, 1984, Patent No. 106541
[15] CORNEAL PERMEATION OF TOPICAL PILOCARPINE NITRATE IN RABBIT
CHRAI, SS
ROBINSON, JR
[J]. AMERICAN JOURNAL OF OPHTHALMOLOGY, 1974, 77 (05) : 735 - 739
[16] KINETICS OF HYDROLYSIS OF PILOCARPINE IN AQUEOUS SOLUTION
CHUNG, PH
CHIN, TF
LACH, JL
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1970, 59 (09) : 1300 - +
[17] DIACETYL DERIVATIVE OF NADOLOL .1. OCULAR PHARMACOLOGY AND SHORT-TERM OCULAR HYPOTENSIVE EFFECT IN GLAUCOMATOUS EYES
DUZMAN, E
CHEN, CC
ANDERSON, J
BLUMENTHAL, M
TWIZER, H
[J]. ARCHIVES OF OPHTHALMOLOGY, 1982, 100 (12) : 1916 - 1919
[18] GLAUCOMA PATIENTS NOT COMPLIANT WITH THEIR DRUG-THERAPY - CLINICAL AND BEHAVIORAL-ASPECTS
GRANSTROM, PA
[J]. BRITISH JOURNAL OF OPHTHALMOLOGY, 1982, 66 (07) : 464 - 470
[19] RELATIONSHIP OF CHEMICAL-STRUCTURE TO CORNEAL PENETRATION AND INFLUENCE OF LOW-VISCOSITY SOLUTION ON OCULAR BIOAVAILABILITY
GRASS, GM
ROBINSON, JR
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1984, 73 (08) : 1021 - 1027
[20] CORRELATIONS BETWEEN ALKANE WATER AND OCTAN-L-OL WATER DISTRIBUTION COEFFICIENTS AND ISOCRATIC REVERSED-PHASE LIQUID-CHROMATOGRAPHIC CAPACITY FACTORS OF ACIDS, BASES AND NEUTRALS
HAFKENSCHEID, TL
TOMLINSON, E
[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1983, 16 (02) : 225 - 239

← 1 2 3 4 5 →