SYNTHETIC RIBONUCLEOTIDE ANALOGS FOR RNA STRUCTURE-FUNCTION STUDIES

被引：4

作者：

GAIT, MJ

GRASBY, JA

KARN, J

MERSMANN, K

PRITCHARD, GE

机构：

[1] Medical Research Council, Laboratory of Molecular Biology, Cambridge, CB2 2QH, Hills Road

[2] Krebs Institute, Department of Chemistry, Sheffield University, Sheffield

[3] Department of Biochemistry, University of Oxford

来源：

NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 3-5期

关键词：

D O I：

10.1080/15257779508012549

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The use of synthetic ribonucleotide analogues in structure-function analysis of RNA is reviewed with particular reference to the roles of specific RNA functional groups in hammerhead ribozyme cleavage and in the interactions of the HIV-1 gene regulatory proteins tat and rev with their respective RNA targets TAR and RRE.

引用

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页码：1133 / 1144

页数：12

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