SYNTHESIS OF PSEUDO-DISACCHARIDES RELATED TO ALLOSAMIDIN

被引：18

作者：

CORBETT, DF ^{[1
]}

DEAN, DK ^{[1
]}

ROBINSON, SR ^{[1
]}

机构：

[1] SMITHKLINE BEECHAM PHARMACEUT,EPSOM KT18 5XQ,SURREY,ENGLAND

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 03期

关键词：

PSEUDO-DISACCHARIDES; ALLOSAMIDIN; GLUCOALLOSAMIDIN; CHITINASE INHIBITOR; STEREOSPECIFIC BETA-1,4-GLYCOSIDATION;

D O I：

10.1016/0040-4039(94)85080-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Suitably protected carbocyclic pseudo-sugars were synthesised from D-glucosamine via a Ferrier rearrangement. Stereospecific coupling with the glycosyl donor, 1,3,4,6-retra-O-acetyl-2-deoxy-2-phthalimido-beta-D-glucopyranoside and subsequent protecting group interconversions furnished beta-1,4- pseudo-disaccharides related to the chitinase inhibitor, allosamidin.

引用

页码：459 / 462

页数：4

共 13 条

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