CALCIUM-PHOSPHATE PRECIPITATION ON THE SURFACE OF HA-G-TI COMPOSITE UNDER PHYSIOLOGICAL CONDITIONS

被引:22
作者
BAN, S
MARUNO, S
IWATA, H
ITOH, H
机构
[1] NAGOYA INST TECHNOL, SHOWA KU, NAGOYA, AICHI 466, JAPAN
[2] NAGOYA UNIV, FAC MED, SHOWA KU, NAGOYA, AICHI 466, JAPAN
[3] TOKYO KOUSEINENKIN HOSP, SHINJUKU KU, TOKYO, TOKYO 162, JAPAN
来源
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH | 1994年 / 28卷 / 01期
关键词
D O I
10.1002/jbm.820280109
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Hydroxyapatite-glass-titanium (HA-G-Ti) functionally gradient composite plates bound face-to-face by nylon wire were soaked in a simulated body fluid. The gap between the plates was filled with the precipitates after soaking for 6 months, and a tight chemical bond was formed between them. Field emission-type (FE) scanning electron microscopy (SEM) and transmission electron microscopy observations revealed that the growth rate and morphology of the precipitates differed widely from the outside portion to the inside one on the surface region of the composite plates. In the portion relatively near the outside, the mutually bonded portion, needle-like precipitates with preferred orientation to the c-axis were markedly observed. From the results of Fourier transform infrared spectroscopy and energy dispersive x-ray microanalysis, it was found that the precipitates were Ca-deficient carbonate apatite with low crystallinity. On the other hand, HA-G-Ti composite rods were implanted in the femur of beagle dogs for 3 months. FE-SEM observations demonstrated that needle-like precipitates were deposited on both the surfaces of the composite and bone at the portion having a narrow gap, about 0.1-0.2 mm between them prepared deliberately before implantation. It was found that both the morphologies and the composition of the precipitates in vivo were similar to those in vitro. It is concluded that the HA particles on the surface of the composite act as nucleation sites for precipitation in physiologic environments, whereas the glass matrix is independent to it. (C) 1994 John Wiley and Sons, Inc.
引用
收藏
页码:65 / 71
页数:7
相关论文
共 17 条
  • [11] IWATA H, 1989, BIOCERAMICS, P411
  • [12] COMPOSITIONAL DEPENDENCE OF FORMATION OF AN APATITE LAYER ON GLASS-CERAMICS IN SIMULATED PHYSIOLOGICAL SOLUTION
    KASUGA, T
    NAKAGAWA, K
    YOSHIDA, M
    MIYADE, E
    [J]. JOURNAL OF MATERIALS SCIENCE, 1987, 22 (10) : 3721 - 3724
  • [13] KOKUBO T, 1987, YOGYO-KYOKAI-SHI, V95, P785
  • [14] LEGEROS RZ, 1992, 4TH T WORLD BIOM C B, P328
  • [15] MICRO-OBSERVATION AND CHARACTERIZATION OF BONDING BETWEEN BONE AND HA-GLASS-TITANIUM FUNCTIONALLY GRADIENT COMPOSITE
    MARUNO, S
    ITOH, H
    BAN, S
    IWATA, H
    ISHIKAWA, T
    [J]. BIOMATERIALS, 1991, 12 (02) : 225 - 230
  • [16] Properties of functionally gradient composite consisting of hydroxyapatite containing glass coated titanium and characters for bioactive implant
    Maruno, Shigeo
    Ban, Seiji
    Wang, Yun-Fu
    Iwata, Hisashi
    Itoh, Haruo
    [J]. Nippon Seramikkusu Kyokai Gakujutsu Ronbunshi/Journal of the Ceramic Society of Japan, 1992, 100 (1160): : 362 - 367
  • [17] WANG Y, 1986, OCT ANN M JAP I MET