NOVEL BIOPOLYMERS FOR DRUG DISCOVERY

被引：59

作者：

MORAN, EJ ^{[1
]}

WILSON, TE ^{[1
]}

CHO, CY ^{[1
]}

CHERRY, SR ^{[1
]}

SCHULTZ, PG ^{[1
]}

机构：

[1] UNIV CALIF BERKELEY,DEPT CHEM,BERKELEY,CA 94720

来源：

BIOPOLYMERS | 1995年 / 37卷 / 03期

关键词：

D O I：

10.1002/bip.360370305

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The solid phase synthesis and generation of libraries of ''unnatural biopolymers'' is described. These polymers are characterized by novel backbones and building blocks, the properties of which may modify their pharmacological and folding properties (C) 1995 John Wiley & Sons, Inc.

引用

收藏

页码：213 / 219

页数：7

相关论文

共 55 条

[31] THE USE OF DIETHYL AZODICARBOXYLATE AND TRIPHENYLPHOSPHINE IN SYNTHESIS AND TRANSFORMATION OF NATURAL-PRODUCTS [J].

MITSUNOBU, O .

SYNTHESIS-STUTTGART, 1981, (01) :1-28

[32] GENERATION AND SCREENING OF AN OLIGONUCLEOTIDE-ENCODED SYNTHETIC PEPTIDE LIBRARY [J].

NEEDELS, MC ;

JONES, DG ;

TATE, EH ;

HEINKEL, GL ;

KOCHERSPERGER, LM ;

DOWER, WJ ;

BARRETT, RW ;

GALLOP, MA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (22) :10700-10704

[33] SYNTHETIC METHODS FOR THE IMPLEMENTATION OF ENCODED COMBINATORIAL CHEMISTRY [J].

NIELSEN, J ;

BRENNER, S ;

JANDA, KD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (21) :9812-9813

[34] REDUCTION OF CARBOXYLIC-ACIDS TO ALCOHOLS THROUGH 1-SUCCINIMIDYL ESTERS WITH NABH4 [J].

NIKAWA, J ;

SHIBA, T .

CHEMISTRY LETTERS, 1979, (08) :981-982

[35] COMPLEX SYNTHETIC CHEMICAL LIBRARIES INDEXED WITH MOLECULAR TAGS [J].

OHLMEYER, MHJ ;

SWANSON, RN ;

DILLARD, LW ;

READER, JC ;

ASOULINE, G ;

KOBAYASHI, R ;

WIGLER, M ;

STILL, WC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (23) :10922-10926

[36]

PATCHORNIK CA, 1970, J AM CHEM SOC, V92, P6333

[37] CONFORMATIONALLY RESTRICTED ANALOGS OF SOMATOSTATIN WITH HIGH MU-OPIATE RECEPTOR SPECIFICITY [J].

PELTON, JT ;

GULYA, K ;

HRUBY, VJ ;

DUCKLES, SP ;

YAMAMURA, HI .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (01) :236-239

[38] TETRABUTYLAMMONIUM BOROHYDRIDE - BOROHYDRIDE REDUCTIONS IN DICHLOROMETHANE [J].

RABER, DJ ;

GUIDA, WC .

JOURNAL OF ORGANIC CHEMISTRY, 1976, 41 (04) :690-696

[39] SOLID-PHASE SYNTHESIS OF PROTECTED PEPTIDE-FRAGMENTS USING A TRIALKOXY-DIPHENYL-METHYLESTER RESIN [J].

RINK, H .

TETRAHEDRON LETTERS, 1987, 28 (33) :3787-3790

[40] A FACILE SYNTHESIS OF CHIRAL N-PROTECTED BETA-AMINO ALCOHOLS [J].

RODRIGUEZ, M ;

LLINARES, M ;

DOULUT, S ;

HEITZ, A ;

MARTINEZ, J .

TETRAHEDRON LETTERS, 1991, 32 (07) :923-926

← 1 2 3 4 5 6 →