SYNTHESIS OF NOVEL, SUBSTITUTED 4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINES

被引：28

作者：

FRYER, RI

GU, ZQ

WANG, CG

机构：

[1] Rutgers, State University of New Jersey, Department of Chemistry, Carl. A. Olson Laboratory, Newark, New Jersey, 07102

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1991年 / 28卷 / 07期

关键词：

D O I：

10.1002/jhet.5570280704

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthetic approaches to novel, substituted 4H-imidazo[1,5-a][1,4]benzodiazepines are described. The compounds prepared are, in general, derivatives of known ring systems and structures were assigned on the basis of spectroscopic evidence.

引用

页码：1661 / 1669

页数：9

共 21 条

[1] SYNTHESIS AND ANTIINFLAMMATORY ACTIVITY OF "1-ALKYL-4-ARYL-2(1H)-QUINAZOLINONES AND QUINAZOLINETHIONES [J].

COOMBS, RV ;

DANNA, RP ;

DENZER, M ;

HARDTMANN, GE ;

HUEGI, B ;

KOLETAR, G ;

KOLETAR, J ;

OTT, H ;

JUKNIEWICZ, E ;

PERRINE, JW ;

TAKESUE, EI ;

TRAPOLD, JH .

JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (11) :1237-1245

[2]

DIXON R, 1982, METHOD ENZYMOL, V84, P490

[3] QUINAZOLINES AND 1,4-BENZODIAZEPINES .89. HAPTENS USEFUL IN BENZODIAZEPINE IMMUNOASSAY DEVELOPMENT [J].

EARLEY, JV ;

FRYER, RI ;

NING, RY .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1979, 68 (07) :845-850

[4] POLYCLONAL ANTIBODIES TO AGONIST BENZODIAZEPINES [J].

FRY, JP ;

RICKETS, C ;

MARTIN, IL .

BIOCHEMICAL PHARMACOLOGY, 1987, 36 (21) :3763-3770

[5] THE RATIONAL DESIGN AND SYNTHESIS OF HAPTENS HAVING SPECIFIC ACTIVITY AS FULL AGONISTS OR FULL ANTAGONISTS AT THE BENZODIAZEPINE RECEPTOR [J].

FRYER, RI ;

GU, ZQ .

LIFE SCIENCES, 1990, 47 (10) :833-840

[6] QUINAZOLINES AND 1,4-BENZODIAZEPINES .73. RING EXPANSION OF 2-CHLOROMETHYLQUINAZOLINE 3-OXIDES WITH NITROMETHANE [J].

FRYER, RI ;

EARLEY, JV ;

GILMAN, NW ;

ZALLY, W .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1976, 13 (03) :433-437

[7] NITRATION PRODUCTS OF SUBSTITUTED 1,3-DIHYDRO-5-PHENYL-2H-1,4-BENZODIAZEPIN-2-ONES [J].

FRYER, RI ;

GU, ZQ ;

TODARO, L .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1991, 28 (05) :1203-1208

[8]

FRYER RI, 1983, J HETEROCYCLIC CHEM, V20, P1650

[9]

FRYER RI, 1972, J HETEROCYCLIC CHEM, V9, P47

[10]

Hansch C, 1990, COMPREHENSIVE MED CH, P539

← 1 2 3 →