MOLECULAR-BASIS OF HEMOPHILIA-B - A DEFECTIVE ENZYME DUE TO AN UNPROCESSED PROPEPTIDE IS CAUSED BY A POINT MUTATION IN THE FACTOR-IX PRECURSOR

被引：122

作者：

DIUGUID, DL ^{[1
]}

RABIET, MJ ^{[1
]}

FURIE, BC ^{[1
]}

LIEBMAN, HA ^{[1
]}

FURIE, B ^{[1
]}

机构：

[1] TUFTS UNIV,SCH MED,BOSTON,MA 02111

来源：

关键词：

D O I：

10.1073/pnas.83.16.5803

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：5803 / 5807

页数：5

共 39 条

[11] BOROWSKI M, 1985, J BIOL CHEM, V260, P9258
[12] BOROWSKI M, 1986, J BIOL CHEM, V261, P1624
[13] CIRCULATING VARIANT OF HUMAN PROALBUMIN
BRENNAN, SO
CARRELL, RW
[J]. NATURE, 1978, 274 (5674) : 908 - 909
[14] MOLECULAR-CLONING OF THE GENE FOR HUMAN ANTI-HEMOPHILIC FACTOR-IX
CHOO, KH
GOULD, KG
REES, DJG
BROWNLEE, GG
[J]. NATURE, 1982, 299 (5879) : 178 - 180
[15] DAVIS LM, 1984, BLOOD S, V64, P262
[16] CHARACTERIZATION OF PROTEIN S, A GAMMA-CARBOXYGLUTAMIC ACID CONTAINING PROTEIN FROM BOVINE AND HUMAN-PLASMA
DISCIPIO, RG
DAVIE, EW
[J]. BIOCHEMISTRY, 1979, 18 (05) : 899 - 904
[17] DIUGUID DL, 1985, BLOOD S, V66, P332
[18] GIANNELLI F, 1983, NATURE, V303, P181, DOI 10.1038/303181a0
[19] QUANTITATIVE-DETERMINATION OF GAMMA-CARBOXYGLUTAMIC ACID IN PROTEINS
HAUSCHKA, PV
[J]. ANALYTICAL BIOCHEMISTRY, 1977, 80 (01) : 212 - 223
[20] HEWICK RM, 1981, J BIOL CHEM, V256, P7990