New antiepileptic drugs: Prospects for the future

被引:13
作者
Britton, JW
So, EL
机构
[1] Division of Epilepsy, Department of Neurology, Mayo Clinic, Rochester, MN
来源
JOURNAL OF EPILEPSY | 1995年 / 8卷 / 04期
关键词
antiepileptic drugs; vigabatrin; lamotrigine; tiagabine; topiramate; zonisamide; oxcarbamazepine; fosphenytoin; pharmacology; pharmacokinetics; epilepsy treatment;
D O I
10.1016/0896-6974(95)00049-6
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Considerable advances have been made in the understanding of the pathophysiology of epilepsy, which has led to the development of a large number of unique antiepileptic drugs affecting a broader array of pharmacological targets than traditional anticonvulsants. In this paper we discuss seven anticonvulsants that are either recently released, or are being actively investigated in the United States. A review of their pharmacological properties and clinical efficacy is presented.
引用
收藏
页码:267 / 281
页数:15
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