New antiepileptic drugs: Prospects for the future

被引：13

作者：

Britton, JW

So, EL

机构：

[1] Division of Epilepsy, Department of Neurology, Mayo Clinic, Rochester, MN

来源：

JOURNAL OF EPILEPSY | 1995年 / 8卷 / 04期

关键词：

antiepileptic drugs; vigabatrin; lamotrigine; tiagabine; topiramate; zonisamide; oxcarbamazepine; fosphenytoin; pharmacology; pharmacokinetics; epilepsy treatment;

D O I：

10.1016/0896-6974(95)00049-6

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Considerable advances have been made in the understanding of the pathophysiology of epilepsy, which has led to the development of a large number of unique antiepileptic drugs affecting a broader array of pharmacological targets than traditional anticonvulsants. In this paper we discuss seven anticonvulsants that are either recently released, or are being actively investigated in the United States. A review of their pharmacological properties and clinical efficacy is presented.

引用

页码：267 / 281

页数：15

共 243 条

[31]

Burton Leslie, 1994, Epilepsia, V35, P116

[32]

CANNON D, 1991, J CHILD NEUROL S2, V8, pS17

[33] ZONISAMIDE-INDUCED MANIA [J].