A FREE-ENERGY PERTURBATION STUDY OF THE BINDING OF METHOTREXATE TO MUTANTS OF DIHYDROFOLATE-REDUCTASE

被引：43

作者：

SINGH, UC ^{[1
]}

BENKOVIC, SJ ^{[1
]}

机构：

[1] PENN STATE UNIV,DEPT CHEM,UNIVERSITY PK,PA 16802

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1988年 / 85卷 / 24期

关键词：

D O I：

10.1073/pnas.85.24.9519

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：9519 / 9523

页数：5

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