CLONING AND SEQUENCE-ANALYSIS OF A MURINE CDNA-ENCODING GLUTAMATE-DECARBOXYLASE (GAD65)

被引：36

作者：

LEE, DS ^{[1
]}

TIAN, JD ^{[1
]}

PHAN, T ^{[1
]}

KAUFMAN, DL ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT PSYCHIAT & BIOBEHAV SCI,760 WESTWOOD PLAZA,LOS ANGELES,CA 90024

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1993年 / 1216卷 / 01期

关键词：

GLUTAMATE DECARBOXYLASE; CDNA; CLONING; GAD; GABA; DIABETES; (NOD MOUSE);

D O I：

10.1016/0167-4781(93)90056-J

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We report the cloning and cDNA sequence of murine GAD65. Murine GAD65 is comprised of 585 amino acids and shares a high degree of homology with human and rat GAD65, with most divergences occurring near their amino-termini. The murine GAD65 sequence will allow evaluation of the role of this gene in murine neurogenetic and autoimmune diseases.

引用

页码：157 / 160

页数：4

共 36 条

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