THE ENIGMATIC CATALYTIC MECHANISM OF ACTIVE-SITE SERINE BETA-LACTAMASES

被引：50

作者：

GALLENI, M

LAMOTTEBRASSEUR, J

RAQUET, X

DUBUS, A

MONNAIE, D

KNOX, JR

FRERE, JM

机构：

[1] UNIV LIEGE,INST CHIM B6,CTR INGN PROT,B-4000 LIEGE,BELGIUM

[2] UNIV LIEGE,INST CHIM B6,ENZYMOL LAB,B-4000 LIEGE,BELGIUM

[3] UNIV CONNECTICUT,DEPT MOLEC & CELL BIOL,STORRS,CT 06269

来源：

BIOCHEMICAL PHARMACOLOGY | 1995年 / 49卷 / 09期

关键词：

ANTIBIOTICS; BETA-LACTAMASES; PENICILLINS; CEPHALOSPORINS; BACTERIAL RESISTANCE; BACTERIAL CELL WALL;

D O I：

10.1016/0006-2952(94)00502-D

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

[No abstract available]

引用

页码：1171 / 1178

页数：8

共 45 条

[11] LEAVING GROUP SPECIFICITY IN CHYMOTRYPSIN-CATALYZED HYDROLYSIS OF PEPTIDES - STEREOCHEMICAL INTERPRETATION [J].

FERSHT, AR ;

BLOW, DM ;

FASTREZ, J .

BIOCHEMISTRY, 1973, 12 (11) :2035-2041

[12]

Frere J.M., 1992, CHEM BETA LACTAMS, P148

[13]

FRERE JM, 1985, CRC CR REV MICROBIOL, V11, P299

[14] QUANTITATIVE RELATIONSHIP BETWEEN SENSITIVITY TO BETA-LACTAM ANTIBIOTICS AND BETA-LACTAMASE PRODUCTION IN GRAM-NEGATIVE BACTERIA .2. NON-STEADY-STATE TREATMENT AND PROGRESS CURVES [J].

FRERE, JM ;

JORIS, B ;

CRINE, M ;

MARTIN, HH .

BIOCHEMICAL PHARMACOLOGY, 1989, 38 (09) :1427-1433

[15] USE OF THE CHROMOSOMAL CLASS-A BETA-LACTAMASE OF MYCOBACTERIUM-FORTUITUM D316 TO STUDY POTENTIALLY POOR SUBSTRATES AND INHIBITORY BETA-LACTAM COMPOUNDS [J].

GALLENI, M ;

FRANCESCHINI, N ;

QUINTING, B ;

FATTORINI, L ;

OREFICI, G ;

ORATORE, A ;

FRERE, JM ;

AMICOSANTE, G .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1994, 38 (07) :1608-1614

[16] A SURVEY OF THE KINETIC-PARAMETERS OF CLASS-C BETA-LACTAMASES - CEPHALOSPORINS AND OTHER BETA-LACTAM COMPOUNDS [J].

GALLENI, M ;

AMICOSANTE, G ;

FRERE, JM .

BIOCHEMICAL JOURNAL, 1988, 255 (01) :123-129

[17] SITE-DIRECTED MUTAGENESIS OF BETA-LACTAMASE-I - SINGLE AND DOUBLE MUTANTS OF GLU-166 AND LYS-73 [J].

GIBSON, RM ;

CHRISTENSEN, H ;

WALEY, SG .

BIOCHEMICAL JOURNAL, 1990, 272 (03) :613-619

[18]

HECHLER U, 1989, J GEN MICROBIOL, V135, P1275

[19] REFINED CRYSTAL-STRUCTURE OF BETA-LACTAMASE FROM STAPHYLOCOCCUS-AUREUS PC1 AT 2.0-A RESOLUTION [J].

HERZBERG, O .

JOURNAL OF MOLECULAR BIOLOGY, 1991, 217 (04) :701-719

[20] STRUCTURAL BASIS FOR THE INACTIVATION OF THE P54 MUTANT OF BETA-LACTAMASE FROM STAPHYLOCOCCUS-AUREUS PC1 [J].

HERZBERG, O ;

KAPADIA, G ;

BLANCO, B ;

SMITH, TS ;

COULSON, A .

BIOCHEMISTRY, 1991, 30 (39) :9503-9509

← 1 2 3 4 5 →