THE MOLECULAR-BASIS OF MOISTURE EFFECTS ON THE PHYSICAL AND CHEMICAL-STABILITY OF DRUGS IN THE SOLID-STATE

被引：423

作者：

AHLNECK, C ^{[1
]}

ZOGRAFI, G ^{[1
]}

机构：

[1] UNIV WISCONSIN, SCH PHARM, MADISON, WI 53706 USA

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1990年 / 62卷 / 2-3期

关键词：

Crystal defect; Drug-excipient interaction; Glass transition; Moisture sorption; Molecular mobility; Solid-state degradation; Solid-state transition; Water sorption;

D O I：

10.1016/0378-5173(90)90221-O

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

[No abstract available]

引用

页码：87 / 95

页数：9

共 61 条

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