THE GENE ENCODING MYELOID ALPHA-3-FUCOSYLTRANSFERASE(FUT4) IS LOCATED BETWEEN D11S388 AND D11S919 ON 11Q21

被引：26

作者：

REGUIGNE, I

JAMES, MR

RICHARD, CW

MOLLICONE, R

SEAWRIGHT, A

LOWE, JB

ORIOL, R

COUILLIN, P

机构：

[1] INSERM,U358,PARIS,FRANCE

[2] CEPH,PARIS,FRANCE

[3] UNIV PITTSBURGH,DEPT PSYCHIAT,PITTSBURGH,PA

[4] UNIV PITTSBURGH,DEPT HUMAN GENET,PITTSBURGH,PA

[5] WESTERN GEN HOSP,MRC,HUMAN GENET UNIT,EDINBURGH EH4 2XU,MIDLOTHIAN,SCOTLAND

[6] HOWARD HUGHES MED INST,ANN ARBOR,MI

来源：

CYTOGENETICS AND CELL GENETICS | 1994年 / 66卷 / 02期

关键词：

D O I：

10.1159/000133677

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The last step in the biosynthesis of Le(x) antigen, the addition of a fucose to precursor polysaccharides, can be catalyzed by different alpha-3-fucosyltransferases. We localized the gene (FUT4) encoding myeloid alpha-3-fucosyltransferase by PCR assay using panels of somatic cell and radiation hybrids which retain different rearrangements of chromosome 11. FUT4 was assigned to chromosome band 11q21 between D11S388 and D11S919.

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页码：104 / 106

页数：3

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