P-GLYCOPROTEIN - TO FLIP OR NOT TO FLIP

被引：21

作者：

HIGGINS, CF ^{[1
]}

机构：

[1] UNIV OXFORD,JOHN RADCLIFFE HOSP,NUFFIELD DEPT CLIN BIOCHEM,OXFORD OX3 9DU,ENGLAND

来源：

CURRENT BIOLOGY | 1994年 / 4卷 / 03期

关键词：

D O I：

10.1016/S0960-9822(00)00059-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The phenotype of mice homozygous for mutations of the mdr2 gene suggests that the mdr2 protein, which is closely related to the multidrug resistance P-nglycoprotein, has a role in phospholipid transport. © 1994 Elsevier Science Ltd. All rights reserved.

引用

页码：259 / 260

页数：2

共 7 条

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[3] IS THE MULTIDRUG TRANSPORTER A FLIPPASE
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[7] HOMOZYGOUS DISRUPTION OF THE MURINE MDR2 P-GLYCOPROTEIN GENE LEADS TO A COMPLETE ABSENCE OF PHOSPHOLIPID FROM BILE AND TO LIVER-DISEASE
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SCHINKEL, AH
ELFERINK, RPJO
GROEN, AK
WAGENAAR, E
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OTTENHOFF, R
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[J]. CELL, 1993, 75 (03) : 451 - 462

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