THE CHEMICAL SYNTHESIS OF LEISHMANIA-DONOVANI PHOSPHOGLYCAN VIA POLYCONDENSATION OF A GLYCOBIOSYL HYDROGENPHOSPHONATE MONOMER

被引：38

作者：

NIKOLAEV, AV

CHUDEK, JA

FERGUSON, MAJ

机构：

[1] UNIV DUNDEE,DEPT BIOCHEM,DUNDEE DD1 4HN,SCOTLAND

[2] UNIV DUNDEE,DEPT CHEM,DUNDEE DD1 4HN,SCOTLAND

来源：

CARBOHYDRATE RESEARCH | 1995年 / 272卷 / 02期

基金：

英国惠康基金;

关键词：

SYNTHESIS; PHOSPHOGLYCAN; LEISHMANIA; GLYCOSYL H-PHOSPHONATE;

D O I：

10.1016/0008-6215(95)00067-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A polycondensation of 2,3,6-tri-O-benzoyl-4-O-(2,3,4-tri-O-benzoyl-beta-D-galactopyranosyl)-alpha-D-mannopyranosyl hydrogenphosphonate in the presence of trimethylacetyl chloride has been used to synthesize a linear poly[ beta-D-galactopyranosyl-(1-,4)-alpha-D-mannopyranosyl phosphate] representing the phosphoglycan part of the lipophosphoglycan from Leishmania donovani.

引用

页码：179 / 189

页数：11

共 8 条

[1] Ferguson M. A. J., 1992, LIPID MODIFICATION P, P191
[2] Kenne L., 1983, POLYSACCHARIDES, P287
[3] THE STRUCTURE, BIOSYNTHESIS AND FUNCTION OF GLYCOSYLATED PHOSPHATIDYLINOSITOLS IN THE PARASITIC PROTOZOA AND HIGHER EUKARYOTES
MCCONVILLE, MJ
FERGUSON, MAJ
[J]. BIOCHEMICAL JOURNAL, 1993, 294 : 305 - 324
[4] THE CHEMICAL SYNTHESIS OF LEISHMANIA-DONOVANI PHOSPHOGLYCAN FRAGMENTS
NIKOLAEV, AV
RUTHERFORD, TJ
FERGUSON, MAJ
BRIMACOMBE, JS
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1994, 4 (06) : 785 - 788
[5] THE STEPWISE SYNTHESIS OF OLIGO(GLYCOSYL PHOSPHATES) VIA GLYCOSYL HYDROGENPHOSPHONATES - THE CHEMICAL SYNTHESIS OF OLIGOMERIC FRAGMENTS FROM HANSENULA-CAPSULATA Y-1842 EXOPHOSPHOMANNAN AND FROM ESCHERICHIA-COLI K51 CAPSULAR ANTIGEN
NIKOLAEV, AV
IVANOVA, IA
SHIBAEV, VN
[J]. CARBOHYDRATE RESEARCH, 1993, 242 : 91 - 107
[6] NIKOLAEV AV, 1992, BIOORG KHIM+, V18, P272
[7] NIKOLAEV AV, 1994, 17TH INT CARB S OTT, P256
[8] ALPHA-GLYCOPYRANOSYL AND BETA-GLYCOPYRANOSYL PHOSPHATES AND 1,2-PHOSPHATES - ASSIGNMENTS OF CONFORMATIONS IN SOLUTION BY C-13 AND H-1 NMR
OCONNOR, JV
NUNEZ, HA
BARKER, R
[J]. BIOCHEMISTRY, 1979, 18 (03) : 500 - 507

← 1 →