2-ACETAMIDO-1,2-DIDEOXYNOJIRIMYCIN - AN IMPROVED SYNTHESIS

被引：28

作者：

FURNEAUX, RH

GAINSFORD, GJ

LYNCH, GP

YORKE, SC

机构：

[1] Industrial Research Limited, Lower Hutt

来源：

TETRAHEDRON | 1993年 / 49卷 / 42期

关键词：

D O I：

10.1016/S0040-4020(01)80229-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The potent beta-N-acetylglucosaminidase inhibitor, 2-acetamido-1,2-dideoxynojirimycin, was prepared in 6 steps from N-acetyl-D-glucosamine (overall yield 10%) via the double reductive amination of a keto aldehyde as the key step.

引用

页码：9605 / 9612

页数：8

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