CLINICAL AND PRECLINICAL PHOTODYNAMIC THERAPY

被引:363
作者
FISHER, AMR
MURPHREE, AL
GOMER, CJ
机构
[1] UNIV SO CALIF, SCH MED, DEPT PEDIAT, LOS ANGELES, CA 90027 USA
[2] UNIV SO CALIF, SCH MED, DEPT OPHTHALMOL, LOS ANGELES, CA 90027 USA
[3] UNIV SO CALIF, SCH MED, DEPT RADIAT ONCOL, LOS ANGELES, CA 90027 USA
关键词
PHOTODYNAMIC THERAPY; PHOTOMEDICINE; PHOTOSENSITIZERS; PHOTOFRIN; LASERS; TUMOR; OXIDATIVE STRESS;
D O I
10.1002/lsm.1900170103
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Photodynamic therapy (PDT) is a treatment modality that utilizes a photosensitizing drug activated by laser generated light, and is proving effective for oncologic and nononcologic applications. This report provides an overview of photosensitizers, photochemistry, photobiology, and the lasers involved in photodynamic therapy. Clinical and preclinical PDT studies involving Photofrin and various second generation photosensitizers are reviewed. (C) 1995 Wiley-Liss, Inc.
引用
收藏
页码:2 / 31
页数:30
相关论文
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