学术探索
学术期刊
新闻热点
数据分析
智能评审

CLINICAL AND PRECLINICAL PHOTODYNAMIC THERAPY

被引：363
作者：
FISHER, AMR
MURPHREE, AL
GOMER, CJ
机构：
[1] UNIV SO CALIF, SCH MED, DEPT PEDIAT, LOS ANGELES, CA 90027 USA
[2] UNIV SO CALIF, SCH MED, DEPT OPHTHALMOL, LOS ANGELES, CA 90027 USA
[3] UNIV SO CALIF, SCH MED, DEPT RADIAT ONCOL, LOS ANGELES, CA 90027 USA
来源：
LASERS IN SURGERY AND MEDICINE | 1995年 / 17卷 / 01期
关键词：
PHOTODYNAMIC THERAPY; PHOTOMEDICINE; PHOTOSENSITIZERS; PHOTOFRIN; LASERS; TUMOR; OXIDATIVE STRESS;
D O I：
10.1002/lsm.1900170103
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Photodynamic therapy (PDT) is a treatment modality that utilizes a photosensitizing drug activated by laser generated light, and is proving effective for oncologic and nononcologic applications. This report provides an overview of photosensitizers, photochemistry, photobiology, and the lasers involved in photodynamic therapy. Clinical and preclinical PDT studies involving Photofrin and various second generation photosensitizers are reviewed. (C) 1995 Wiley-Liss, Inc.
引用
收藏
页码：2 / 31
页数：30
相关论文
共 196 条
  • [81] Reed MWR, Wieman TJ, Schuske DA, Tseng MT, Miller FN, A comparison of the effects of photodynamic therapy on normal and tumor blood vessels in the rat microcirculation, Rad Res, 119, pp. 542-552, (1989)
  • [82] Henderson BW, Dougherty TJ, How does photodynamic therapy work, Photochem Photobiol, 55, pp. 145-157, (1992)
  • [83] Moan J, Berg K, Photochemotherapy of cancer: Experimental research, Photochem Photobiol, 55, pp. 931-948, (1992)
  • [84] Oseroff AR, Ohuoha D, Ara G, McAuliffe D, Foley J, Cincotta L, Intramitochondrial dyes allow selective in vitro photolysis of carcinoma cells, PNAS (USA), 83, pp. 9729-9733, (1986)
  • [85] Chan WS, Marshall JF, Hart IR, Effect of tumor location on selective uptake and retention of phthalocyanines, Cancer Lett, 44, pp. 73-77, (1989)
  • [86] Jain RK, Transport of molecules in the tumor interstitium: A review, Cancer Res, 47, pp. 3039-3051, (1987)
  • [87] Kessel D, Porphyrinlipoprotein association as a factor in porphyrin localization, Cancer Lett, 33, pp. 183-188, (1986)
  • [88] Kaye AH, Hill JS, Photoradiation therapy of brain tumors: Laboratory and clinical studies, Phototherapy of Cancer, pp. 101-118, (1990)
  • [89] Mang TS, Dougherty TJ, Time and sequence dependent influence of in vivo photodynamic therapy survival by hyperthermia, Photochem Photobiol, 42, pp. 533-540, (1985)
  • [90] Waldow SM, Henderson BW, Dougherty TJ, Potentiation of photodynamic therapy by heat: Effect of sequence and time interval between treatments in vivo, Lasers Surg Med, 5, pp. 83-94, (1985)
45678910111213