SYNTHETIC STUDY OF MARINE MACROLIDE SWINHOLIDE-A - STEREOCONTROLLED SYNTHESIS OF THE C-11-C23 SEGMENT

被引：21

作者：

NAKATA, T ^{[1
]}

KOMATSU, T ^{[1
]}

NAGASAWA, K ^{[1
]}

YAMADA, H ^{[1
]}

TAKAHASHI, T ^{[1
]}

机构：

[1] TOKYO INST TECHNOL,MEGURO KU,TOKYO 152,JAPAN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 44期

关键词：

D O I：

10.1016/0040-4039(94)88288-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The C11-C23 segment 4 of swinholide A (1) was synthesized stereoselectively starting from (S)-malic acid via double nitroaldol reaction under high pressure and differentiation of the left and right parts of the symmetric compound 10 as the key steps.

引用

页码：8225 / 8228

页数：4

共 16 条

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