FURTHER INSIGHT INTO THE MODE OF ACTION OF THE NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP)

被引：32

作者：

GESSNER, W ^{[1
]}

BROSSI, A ^{[1
]}

SHEN, RS ^{[1
]}

ABELL, CW ^{[1
]}

机构：

[1] UNIV TEXAS,MED BRANCH,DEPT HUMAN BIOL CHEM & GENET,DIV BIOCHEM,GALVESTON,TX 77550

来源：

FEBS LETTERS | 1985年 / 183卷 / 02期

关键词：

D O I：

10.1016/0014-5793(85)80807-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：345 / 348

页数：4

共 22 条

[1] METABOLISM OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) IN MOUSE-LIVER PREPARATIONS [J].

BAKER, JK ;

BORNE, RF ;

DAVIS, WM ;

WATERS, IW .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 125 (02) :484-490

[2]

BROSSI A, 1984, 8TH P S CHEM HET COM, P63

[3] POTENTIAL BIOACTIVATION PATHWAYS FOR THE NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) [J].

CASTAGNOLI, N ;

CHIBA, K ;

TREVOR, AJ .

LIFE SCIENCES, 1985, 36 (03) :225-230

[4] METABOLISM OF THE NEUROTOXIC TERTIARY AMINE, MPTP, BY BRAIN MONOAMINE-OXIDASE [J].

CHIBA, K ;

TREVOR, A ;

CASTAGNOLI, N .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 120 (02) :574-578

[5] STUDIES ON THE MECHANISM OF ACTION OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) [J].

COHEN, G ;

MYTILINEOU, C .

LIFE SCIENCES, 1985, 36 (03) :237-242

[6] INHIBITION OF DOPAMINE UPTAKE BY N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE, A CAUSE OF PARKINSONISM [J].

DENTON, T ;

HOWARD, BD .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 119 (03) :1186-1190

[7] CONVERSION OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) AND ITS 5-METHYL ANALOG INTO PYRIDINIUM SALTS [J].

GESSNER, W ;

BROSSI, A ;

SHEN, RS ;

FRITZ, RR ;

ABELL, CW .

HELVETICA CHIMICA ACTA, 1984, 67 (08) :2037-2042

[8]

GESSNER W, UNPUB

[9]

GIERSON DS, 1980, J AM CHEM SOC, V102, P1064

[10]

GRAY EG, 1962, J ANAT, V96, P79

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