ARF - A KEY REGULATORY SWITCH IN MEMBRANE TRAFFIC AND ORGANELLE STRUCTURE

被引：239

作者：

DONALDSON, JG

KLAUSNER, RD

机构：

[1] Cell Biology and Metabolism Branch, NICHD, National Institutes of Health, Bethesda, MD 20892, Bldg. 18T, Room 101

来源：

CURRENT OPINION IN CELL BIOLOGY | 1994年 / 6卷 / 04期

关键词：

D O I：

10.1016/0955-0674(94)90072-8

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The small GTP-binding protein ADP ribosylation factor (ARF) regulates, through a GTP cycle, the reversible binding of cytosolic coat proteins to Golgi membranes. By determining the binding and release of coat proteins from membranes, ARF controls the production and lifetime of coated-membrane structures. In the past year, studies suggesting a role for ARF in phospholipid metabolism have broadened our perspective on ARF function within the cell.

引用

页码：527 / 532

页数：6

共 54 条

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