A STUDY OF THE BIOLOGICALLY-ACTIVE CONFORMERS FOR PRODINE OPIATES AND THEIR DERIVATIVES

被引：16

作者：

FROIMOWITZ, M ^{[1
]}

KOLLMAN, P ^{[1
]}

机构：

[1] UNIV CALIF SAN FRANCISCO,SCH PHARM,DEPT PHARMACEUT CHEM,SAN FRANCISCO,CA 94143

来源：

JOURNAL OF COMPUTATIONAL CHEMISTRY | 1984年 / 5卷 / 06期

关键词：

D O I：

10.1002/jcc.540050602

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：507 / 516

页数：10

共 40 条

[11] STRUCTURAL STUDIES OF SYNTHETIC ANALGETICS .2. CRYSTAL AND MOLECULAR STRUCTURE OF MONOCLINIC FORM OF (+/-)-BETA-PROMEDOL ALCOHOL [J].

DECAMP, WH ;

AHMED, FR .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL CRYSTALLOGRAPHY AND CRYSTAL CHEMISTRY, 1972, B 28 (06) :1796-&

[12] CRITICAL EVALUATION OF MOLECULAR MECHANICS [J].

ENGLER, EM ;

ANDOSE, JD ;

SCHLEYER, PV .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1973, 95 (24) :8005-8025

[13] STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS .18. ABSOLUTE-CONFIGURATION AND ANALGETIC POTENCY OF TRIMEPERIDINE ENANTIOMERS [J].

FRIES, D ;

PORTOGHE.PS .

JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (09) :990-993

[14] STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS .20. ABSOLUTE-CONFIGURATION AND ANALGETIC POTENCY OF ALPHA-PROMEDOL ENANTIOMERS - ROLE OF C-4 CHIRAL CENTER IN CONFERRING STEREOSELECTIVITY IN AXIAL-PHENYL AND EQUATORIAL-PHENYL PRODINE CONGENERS [J].

FRIES, DS ;

PORTOGHESE, PS .

JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (09) :1155-1158

[15] STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS .25. ABSOLUTE-CONFIGURATION AND ANALGETIC POTENCY OF BETA-1,2-DIMETHYL-4-PHENYL-4-(PROPIONYLOXY)PIPERIDINE ENANTIOMERS [J].

FRIES, DS ;

DODGE, RP ;

HOPE, H ;

PORTOGHESE, PS .

JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (01) :9-12

[16]

FROIMOWITZ M, 1983, MOL PHARMACOL, V24, P243

[17] CONFORMATION-ACTIVITY STUDY OF METHADONE AND RELATED-COMPOUNDS [J].

FROIMOWITZ, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (06) :689-696

[18] CONFORMATIONAL PROPERTIES OF ALPHA-AZABICYCLANE AND BETA-AZABICYCLANE OPIATES - THE EFFECT OF CONFORMATION ON PHARMACOLOGICAL ACTIVITY [J].

FROIMOWITZ, M ;

SALVA, P ;

HITE, GJ ;

GIANUTSOS, G ;

SUZDAK, P ;

HEYMAN, R .

JOURNAL OF COMPUTATIONAL CHEMISTRY, 1984, 5 (04) :291-298

[19] PREFERRED CONFORMERS FOR THE PHARMACOLOGICALLY TYPICAL AND ATYPICAL ANTIPODES OF PHENYLMORPHAN OPIATES [J].

FROIMOWITZ, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1984, 27 (09) :1234-1237

[20] CONFORMATION ACTIVITY STUDY OF 4-PHENYLPIPERIDINE ANALGESICS [J].

FROIMOWITZ, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (10) :1127-1133

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