EXPRESSION OF THE ENDOTHELIN-CONVERTING ENZYME GENE IN HUMAN TISSUES

被引：36

作者：

ROSSI, GP ^{[1
]}

ALBERTIN, G ^{[1
]}

FRANCHIN, E ^{[1
]}

SACCHETTO, A ^{[1
]}

CESARI, M ^{[1
]}

PALU, G ^{[1
]}

PESSINA, AC ^{[1
]}

机构：

[1] UNIV HOSP PADUA,SCH MED,DEPT MICROBIOL,I-35126 PADUA,ITALY

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1995年 / 211卷 / 01期

关键词：

D O I：

10.1006/bbrc.1995.1803

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Based on the cDNA sequence of the human and bovine endothelin converting enzyme (ECE-1) we have developed a novel reverse transcription polymerase chain reaction to investigate the tissue expression of this gene. We were able to specifically detect the gene mRNA starting from very limited amount of tissue in all human as well as bovine tissues examined. Thus, our results confirm a widespread expression of the ECE-1 gene in human tissues, in keeping with the findings in other species, and suggest a major biological role of ECE-1. (C) 1995 Academic Press, Inc.

引用

页码：249 / 253

页数：5

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