STEREODIVERGENT SYNTHESIS OF CIS EPOXIDES DERIVED FROM ASYMMETRIZED 2-ALKENYL-1,3-PROPANEDIOLS

被引：17

作者：

GUANTI, G ^{[1
]}

BANFI, L ^{[1
]}

MERLO, V ^{[1
]}

NARISANO, E ^{[1
]}

THEA, S ^{[1
]}

机构：

[1] CNR,CTR STUDIO CHIM COMPOSTI CICLOALIFATICI & AROMATICI,I-16132 GENOA,ITALY

来源：

TETRAHEDRON | 1993年 / 49卷 / 42期

关键词：

D O I：

10.1016/S0040-4020(01)80220-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cis epoxides of any desired absolute stereochemistry have been obtained in a high enantio- and diastereo-divergent manner via diastereospecific epoxidation of asymmetrized (Z)-2-alkenyl-1,3-propanediols, in turn obtained through a chemoenzymatic route, and a protection-deprotection 'trick' on hydroxy groups.

引用

页码：9501 / 9516

页数：16

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