Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients

被引：6

作者：

Delviks-Frankenberry, Krista A. ^{[1
]}

Chaipan, Chawaree ^{[1
]}

Bagni, Rachel ^{[2
]}

Wyvill, Kathleen ^{[3
]}

Yarchoan, Robert ^{[3
]}

Pathak, Vinay K. ^{[1
]}

机构：

[1] NCI, Viral Mutat Sect, HIV Drug Resistance Program, NIH, Frederick, MD 21702 USA

[2] NCI, Prot Express Lab, SAIC Frederick Inc, Frederick, MD 21702 USA

[3] NCI, HIV & AIDS Malignancy Branch, NIH, Bethesda, MD 20892 USA

来源：

ADVANCES IN VIROLOGY | 2011年 / 2011卷

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1155/2011/797820

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with human prostate cancer and chronic fatigue syndrome. Since retroviruses cause various cancers, and XMRV replication might be facilitated by HIV1 co-infection, we asked whether certain patients with HIV-associated lymphomas are infected with XMRV. Analysis of PMBCs and plasma from 26 patients failed to detect XMRV by PCR, ELISA, or Western blot, suggesting a lack of association between XMRV and AIDS-associated lymphomas.

引用

页数：4

共 24 条

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