Xenotropic Murine Leukemia Virus-Related Virus Prevalence in Patients with Chronic Fatigue Syndrome or Chronic Immunomodulatory Conditions

被引：58

作者：

Henrich, Timothy J. ^{[1
,2
,5
]}

Li, Jonathan Z. ^{[1
,2
,5
]}

Felsenstein, Donna ^{[1
,5
]}

Kotton, Camille N. ^{[1
,5
]}

Plenge, Robert M. ^{[3
,4
,5
]}

Pereyra, Florencia ^{[2
,5
,6
]}

Marty, Francisco M. ^{[2
,5
,7
]}

Lin, Nina H. ^{[1
,5
]}

Grazioso, Paul ^{[1
]}

Crochiere, Danielle M. ^{[1
]}

Eggers, Daniel ^{[1
]}

Kuritzkes, Daniel R. ^{[1
,2
,5
]}

Tsibris, Athe M. N. ^{[1
,2
,5
]}

机构：

[1] Massachusetts Gen Hosp, Div Infect Dis, Cambridge, MA 02139 USA

[2] Brigham & Womens Hosp, Div Infect Dis, Cambridge, MA USA

[3] Brigham & Womens Hosp, Div Allergy, Cambridge, MA USA

[4] Brigham & Womens Hosp, Div Immunol, Cambridge, MA USA

[5] Harvard Univ, Sch Med, Cambridge, MA 02138 USA

[6] Massachusetts Gen Hosp, Ragon Inst, Cambridge, MA 02139 USA

[7] Dana Farber Canc Inst, Boston, MA 02115 USA

来源：

JOURNAL OF INFECTIOUS DISEASES | 2010年 / 202卷 / 10期

基金：

美国国家卫生研究院;

关键词：

PROSTATE-CANCER; XMRV; RETROVIRUS; INFECTION; ABSENCE; BLOOD;

D O I：

10.1086/657168

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We investigated the prevalence of xenotropic murine leukemia virus-related virus (XMRV) among 293 participants seen at academic hospitals in Boston, Massachusetts. Participants were recruited from the following 5 groups of patients: chronic fatigue syndrome (n = 32), human immunodeficiency virus infection (n = 43), rheumatoid arthritis (n = 97), hematopoietic stem-cell or solid organ transplant (n = 26), or a general cohort of patients presenting for medical care (n = 95). XMRV DNA was not detected in any participant samples. We found no association between XMRV and patients with chronic fatigue syndrome or chronic immunomodulatory conditions.

引用

页码：1478 / 1481

页数：4

共 16 条

[1] Failure to Detect the Novel Retrovirus XMRV in Chronic Fatigue Syndrome [J].

Erlwein, Otto ;

Kaye, Steve ;

McClure, Myra O. ;

Weber, Jonathan ;

Wills, Gillian ;

Collier, David ;

Wessely, Simon ;

Cleare, Anthony .

PLOS ONE, 2010, 5 (01)

[2] Xenotropic Murine Leukemia Virus-related Gammaretrovirus in Respiratory Tract [J].

Fischer, Nicole ;

Schulz, Claudia ;

Stieler, Kristin ;

Hohn, Oliver ;

Lange, Christoph ;

Drosten, Christian ;

Aepfelbacher, Martin .

EMERGING INFECTIOUS DISEASES, 2010, 16 (06) :1000-1002

[3] Prevalence of human gammaretrovirus XMRV in sporadic prostate cancer [J].

Fischera, Nicole ;

Hellwinkel, Olaf ;

Schulz, Claudia ;

Chun, Felix K. H. ;

Huland, Hartwig ;

Aepfelbacher, Martin ;

Schlomm, Thorsten .

JOURNAL OF CLINICAL VIROLOGY, 2008, 43 (03) :277-283

[4] Antiviral pathway activation in patients with chronic fatigue syndrome and acute infection [J].

Gow, JW ;

Simpson, K ;

Behan, PO ;

Chaudhuri, A ;

McKay, IC ;

Behan, WMH .

CLINICAL INFECTIOUS DISEASES, 2001, 33 (12) :2080-2081

[5] Absence of xenotropic murine leukaemia virus-related virus in UK patients with chronic fatigue syndrome [J].

Groom, Harriet C. T. ;

Boucherit, Virginie C. ;

Makinson, Kerry ;

Randal, Edward ;

Baptista, Sarah ;

Hagan, Suzanne ;

Gow, John W. ;

Mattes, Frank M. ;

Breuer, Judith ;

Kerr, Jonathan R. ;

Stoye, Jonathan P. ;

Bishop, Kate N. .

RETROVIROLOGY, 2010, 7

[6]

Levy J A, 1978, Curr Top Microbiol Immunol, V79, P111

[7] RETRACTED: Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors (Retracted article. See vol. 109, pg. 346, 2012) [J].

Lo, Shyh-Ching ;

Pripuzova, Natalia ;

Li, Bingjie ;

Komaroff, Anthony L. ;

Hung, Guo-Chiuan ;

Wang, Richard ;

Alter, Harvey J. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (36) :15874-15879

[8] RETRACTED: Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome (Retracted article. See vol. 334, pg. 1636, 2011) [J].

Lombardi, Vincent C. ;

Ruscetti, Francis W. ;

Das Gupta, Jaydip ;

Pfost, Max A. ;

Hagen, Kathryn S. ;

Peterson, Daniel L. ;

Ruscetti, Sandra K. ;

Bagni, Rachel K. ;

Petrow-Sadowski, Cari ;

Gold, Bert ;

Dean, Michael ;

Silverman, Robert H. ;

Mikovits, Judy A. .

SCIENCE, 2009, 326 (5952) :585-589

[9] Instrumenting the health care enterprise for discovery research in the genomic era [J].

Murphy, Shawn ;

Churchill, Susanne ;

Bry, Lynn ;

Chueh, Henry ;

Weiss, Scott ;

Lazarus, Ross ;

Zeng, Qing ;

Dubey, Anil ;

Gainer, Vivian ;

Mendis, Michael ;

Glaser, John ;

Kohane, Isaac .

GENOME RESEARCH, 2009, 19 (09) :1675-1681

[10] Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy [J].

Pereyra, Florencia ;

Addo, Marylyn M. ;

Kaufmann, Daniel E. ;

Liu, Yang ;

Miura, Toshiyuki ;

Rathod, Almas ;

Baker, Brett ;

Trocha, Alicja ;

Rosenberg, Rachel ;

Mackey, Elizabeth ;

Ueda, Peggy ;

Lu, Zhigang ;

Cohen, Daniel ;

Wrin, Terri ;

Petropoulos, Christos J. ;

Rosenberg, Eric S. ;

Walker, Bruce D. .

JOURNAL OF INFECTIOUS DISEASES, 2008, 197 (04) :563-571

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