THE INFLUENCE OF LOW FAT, LOW LACTOSE DIET ON DIARRHEA DURING PELVIC RADIOTHERAPY

被引：24

作者：

BYE, A ^{[1
]}

KAASA, S ^{[1
]}

OSE, T ^{[1
]}

SUNDFOR, K ^{[1
]}

TROPE, C ^{[1
]}

机构：

[1] NORWEGIAN RADIUM HOSP,DEPT MED ONCOL & RADIOTHERAPY,N-0310 OSLO 3,NORWAY

来源：

CLINICAL NUTRITION | 1992年 / 11卷 / 03期

关键词：

D O I：

10.1016/0261-5614(92)90075-2

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

In a prospective clinical trial 143 women undergoing pelvic radiotherapy for gynaecological malignancies, were randomized to receive either a low-fat, low-lactose diet (intervention group) or a regular diet (control group) in order to evaluate the possible impact of diet therapy on radiation induced diarrhoea, nausea and vomiting. The daily number and consistency of stools, use of antidiarrhoeal agents, nausea and vomiting were recorded before radiotherapy was begun (week 0), in the last week of therapy (week 6) and 6 weeks after the end of therapy (week 12). The intervention group used half the amount of antidiarrhoeal agents in week 6, than used by the control group (mean 0.6 tablets per day versus 1.1, p < 0.01). 14 patients (23%) in the intervention group reported diarrhoea, versus 32 (48%) in the control group (p < 0.01). In week 12 there were no differences in the use of antidiarrhoeal agents and the prevalence of diarrhoea between the groups.

引用

页码：147 / 153

页数：7

共 38 条

[31]

Bounous, Le Bel, Shuster, Et al., Dietary protection during radiation therapy, Strahlentherapie, 149, pp. 476-483, (1975)

[32]

Mettler, Romeyke, Brieler, Zur Beeinflussung der para- und postradiologischen Dysbakterie und Strahlenreaktion des Darmes durch Bakterium-Bifidum-Substitutionstherapie, Strahlentherapie, 145, pp. 588-599, (1973)

[33]

Franzen, Hellsing, Henriksson, Littbrand, Managing side-effects in radiotherapy with regard to the gastrointestinal tract, Recent Results in Cancer Research, 108, pp. 127-133, (1988)

[34]

Andersson, Bosaeus, Brummer, Et al., Nutritional and metabolic consequences of extensive bowel resection, Digestive Diseases, 4, pp. 193-202, (1986)

[35]

Yeoh, Lui, Lee, The mechanism of diarrhoea resulting from pelvic and abdominal radiotherapy

[36]

a prospective study using selenium-75 labelled conjugated bile acid and cobalt-58 labelled cyanocobalamin, British Journal of Radiology, 57, pp. 1131-1136, (1984)

[37]

Hulshof, Gooskens, Wedel, Bruning, Food intake in three groups of cancer patients. A prospective study during cancer treatment, Human Nutrition: Applied Nutrition, 41, pp. 23-37, (1987)

[38]

Yeoh, Korowitz, Radiation enteritis, Surgery, Gynecology and Obstetrics, 165, pp. 373-379, (1987)

← 1 2 3 4 →