THE ISOLATION OF MAJUSCULAMIDE-C FROM THE SPONGE PTILOCAULIS-TRACHYS COLLECTED IN ENEWETAK AND DETERMINATION OF THE ABSOLUTE-CONFIGURATION OF THE 2-METHYL-3-AMINOPENTANOIC ACID RESIDUE

被引：26

作者：

WILLIAMS, DE

BURGOYNE, DL

RETTIG, SJ

ANDERSEN, RJ

FATHIAFSHAR, ZR

ALLEN, TM

机构：

[1] UNIV BRITISH COLUMBIA,DEPT CHEM,VANCOUVER V6T 1Z4,BC,CANADA

[2] UNIV ALBERTA,DEPT PHARMACOL,EDMONTON T6G 2H7,ALBERTA,CANADA

[3] UNIV BRITISH COLUMBIA,DEPT OCEANOG,VANCOUVER V6T 1Z4,BC,CANADA

来源：

JOURNAL OF NATURAL PRODUCTS | 1993年 / 56卷 / 04期

关键词：

D O I：

10.1021/np50094a015

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Majusculamide C [1], a cyclic depsipeptide metabolite of the blue-green alga Lyngbya majuscula, has been isolated from the sponge Ptilocaulis trachys collected at Enewetak Atoll in the Marshall Islands. The absolute configuration of the novel beta amino acid 2-methyl-3-aminopentanoic acid (MAP), a component of the structure of 1, has been determined to be 2S,3R.

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收藏

页码：545 / 551

页数：7

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