PRECISE MAPPING OF THE EGF RECEPTOR GENE ON THE HUMAN-CHROMOSOME 7P12 USING AN IMPROVED FISH TECHNIQUE

被引：45

作者：

WANG, Y ^{[1
]}

MINOSHIMA, S ^{[1
]}

SHIMIZU, N ^{[1
]}

机构：

[1] KEIO UNIV,SCH MED,DEPT MOLEC BIOL,35 SHINANOMACHI,SHINJUKU KU,TOKYO 160,JAPAN

来源：

JAPANESE JOURNAL OF HUMAN GENETICS | 1993年 / 38卷 / 04期

关键词：

EGF RECEPTOR; GENE MAPPING; FISH;

D O I：

10.1007/BF01907986

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The gene for epidermal growth factor receptor (EGFR) has been localized to the p14-p12 region of human chromosome 7 by somatic cell hybridization and radioisotope in situ hybridization techniques. In this paper, we report the precise mapping of the EGFR gene to the band p12 of chromosome 7 using a novel method in which fluorescence images from in situ hybridization and Q-banding are computer graphically merged. The novel procedure is described in detail.

引用

页码：399 / 406

页数：8

共 25 条

[1] EPIDERMAL GROWTH-FACTOR RECEPTORS [J].

ADAMSON, ED ;

REES, AR .

MOLECULAR AND CELLULAR BIOCHEMISTRY, 1981, 34 (03) :129-152

[2] GENETICS OF RECEPTORS FOR BIOACTIVE POLYPEPTIDES - EXPRESSION OF THE HUMAN EGF RECEPTOR GENE AND INTERNALIZATION AND PROCESSING OF THE RECEPTOR-BOUND EGF IN HUMAN MOUSE-CELL HYBRIDS [J].

BEHZADIAN, MA ;

SHIMIZU, Y ;

KONDO, I ;

SHIMIZU, N .

SOMATIC CELL GENETICS, 1982, 8 (03) :347-362

[3]

BHATT B, 1990, PRINCIPLE PRACTICE, P149

[4]

DAMJANOV I, 1986, LAB INVEST, V55, P588

[5] NERVE GROWTH-FACTOR RECEPTORS ON HUMAN MELANOMA CELLS IN CULTURE [J].

FABRICANT, RN ;

DELARCO, JE ;

TODARO, GJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (02) :565-569

[6] EXPRESSION OF EPIDERMAL GROWTH-FACTOR (EGF) AND THE EGF RECEPTOR IN HUMAN TISSUES [J].

FUKUYAMA, R ;

SHIMIZU, N .

JOURNAL OF EXPERIMENTAL ZOOLOGY, 1991, 258 (03) :336-343

[7] DETECTION OF VARIATION IN THE RIBOSOMAL-RNA GENE CLUSTERS BY A MODIFIED FLUORESCENCE INSITU HYBRIDIZATION METHOD [J].

FUKUYAMA, R ;

SHIMIZU, N .

JAPANESE JOURNAL OF HUMAN GENETICS, 1992, 37 (02) :139-143

[8] REGIONAL LOCALIZATION OF THE HEPATOCYTE GROWTH-FACTOR (HGF) GENE TO HUMAN CHROMOSOME-7 BAND Q21.1 [J].

FUKUYAMA, R ;

ICHIJOH, Y ;

MINOSHIMA, S ;

KITAMURA, N ;

SHIMIZU, N .

GENOMICS, 1991, 11 (02) :410-415

[9] RELATIONSHIP BETWEEN PRODUCTION OF EPIDERMAL GROWTH-FACTOR RECEPTORS, GENE AMPLIFICATION, AND CHROMOSOME-7 TRANSLOCATION IN VARIANT-A431 CELLS [J].

GILL, GN ;

WEBER, W ;

THOMPSON, DM ;

LIN, C ;

EVANS, RM ;

ROSENFELD, MG ;

GAMOU, S ;

SHIMIZU, N .

SOMATIC CELL AND MOLECULAR GENETICS, 1985, 11 (04) :309-318

[10] SUBLOCALIZATION OF AN INVASION-INDUCING LOCUS AND OTHER GENES ON HUMAN CHROMOSOME-7 [J].

HABETS, GGM ;

VANDERKAMMEN, RA ;

WILLEMSEN, V ;

BALEMANS, M ;

WIEGANT, J ;

COLLARD, JG .

CYTOGENETICS AND CELL GENETICS, 1992, 60 (3-4) :200-205

← 1 2 3 →