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THE ROLE OF RECEPTOR SUBTYPE DIVERSITY IN THE CNS

被引：86
作者：
SCHOFIELD, PR [1 ]
SHIVERS, BD [1 ]
SEEBURG, PH [1 ]
机构：
[1] UNIV HEIDELBERG,CTR MOLEC BIOL,W-6900 HEIDELBERG,GERMANY
来源：
TRENDS IN NEUROSCIENCES | 1990年 / 13卷 / 01期
关键词：
D O I：
10.1016/0166-2236(90)90052-C
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The molecular characterization of neuroreceptors and voltage-gated ion channels has revealed that receptor subtype heterogeneity is a common feature of chemical and electrical signal reception. The use of distinct genes encoding receptor subtypes is a favoured mechanism for generation of this diversity. We propose that the significance of the multiplicity and diversity of signal reception proteins is to increase the information-handling capacity of neurons. This may contribute to neural plasticity. © 1990.
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页码：8 / 11
页数：4
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