A TAYLOR MADE LIPOPHILIC CHLORIN FOR PHOTODYNAMIC TUMOR-THERAPY

被引：21

作者：

MONTFORTS, FP

MEIER, A

HAAKE, G

HOPER, F

机构：

[1] Institut für Organische Chemie, FB 2 Biologie/Chemie, 2800 Bremen 33

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 29期

关键词：

PHOTOSENSITIZERS; DERIVATIVES; COMPONENTS;

D O I：

10.1016/0040-4039(91)80811-J

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new chlorin dicarboxylic acid 3 has been synthesized from the porphyrin 1 by amide acetal Claisen rearrangement. The chemical purity, photophysical properties, and its lipophilicity make the chlorin 3 promising candidate for application in Photodynamic Tumor Therapy (PDT).

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收藏

页码：3481 / 3482

页数：2

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