SERIAL MEASUREMENTS OF NEUROPEPTIDE Y-IN PLASMA FOR MONITORING NEUROBLASTOMA IN CHILDREN

被引:27
作者
RASCHER, W
KREMENS, B
WAGNER, S
FETH, F
HUNNEMAN, DH
LANG, RE
机构
[1] UNIV ESSEN GESAMTHSCH, CHILDRENS HOSP, W-4300 ESSEN 1, GERMANY
[2] UNIV GOTTINGEN, CHILDRENS HOSP, W-3400 GOTTINGEN, GERMANY
[3] UNIV GOTTINGEN, DEPT PHYSIOL, W-3400 GOTTINGEN, GERMANY
关键词
D O I
10.1016/S0022-3476(09)90018-X
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Neuropeptide Y (NPY) was studied as a marker for neuroblastoma in 12 children. All but one patient with neuroblastoma had elevated plasma NPY concentrations at diagnosis. During treatment NPY values returned to normal in 9 of 12 children. All three children without normalization of plasma NPY values died; two of them had a relapse and the third died of toxic effects. Plasma NPY appears to be o sensitive marker of neuroblastoma.
引用
收藏
页码:914 / 916
页数:3
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