AZIDE-CONTAINING OR FLUORINE-CONTAINING 2' AND 3'-AZOLYLURIDINES BY REGIOSELECTIVE OPENING OF 1-(2',3'-ANHYDRO-BETA-D-LYXOFURANOSYL)URACILS

被引：12

作者：

ARIZA, X ^{[1
]}

GARCES, J ^{[1
]}

VILARRASA, J ^{[1
]}

机构：

[1] UNIV BARCELONA III,FAC QUIM,DEPT QUIM ORGAN,E-08028 BARCELONA,SPAIN

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 28期

关键词：

D O I：

10.1016/0040-4039(92)88102-B

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Azide- or fluorine-containing imidazol-1-yl, pyrazol-1-yl, and 1,2,4-triazol-1-yl 2',3'-dideoxyuridines have been synthesised from uridine in 5-6 steps, via <<2',3'-beta-epoxy>> derivatives. Regioselective oxirane-ring openings have been accomplished by appropriate choice of the reaction conditions.

引用

页码：4069 / 4072

页数：4

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