DISULFIDE BOND ENGINEERED INTO T4-LYSOZYME - STABILIZATION OF THE PROTEIN TOWARD THERMAL INACTIVATION

被引：303

作者：

PERRY, LJ

WETZEL, R

机构：

来源：

SCIENCE | 1984年 / 226卷 / 4674期

关键词：

D O I：

10.1126/science.6387910

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：555 / 557

页数：3

共 43 条

[31] DISULFIDE BRIDGES IN GLOBULAR-PROTEINS [J].

THORNTON, JM .

JOURNAL OF MOLECULAR BIOLOGY, 1981, 151 (02) :261-287

[32]

TSUGITA A, 1968, J BIOL CHEM, V243, P391

[33]

TSUGITA A, 1971, ENZYMES, V5, P344

[34]

ULMER KM, 1983, SCIENCE, V219, P666, DOI 10.1126/science.6572017

[35] DIRECTED MUTAGENESIS OF DIHYDROFOLATE-REDUCTASE [J].

VILLAFRANCA, JE ;

HOWELL, EE ;

VOET, DH ;

STROBEL, MS ;

OGDEN, RC ;

ABELSON, JN ;

KRAUT, J .

SCIENCE, 1983, 222 (4625) :782-788

[36] ASSIGNMENT OF THE DISULFIDE BONDS OF LEUKOCYTE INTERFERON [J].

WETZEL, R .

NATURE, 1981, 289 (5798) :606-607

[37] EXPRESSION IN ESCHERICHIA-COLI OF A CHEMICALLY SYNTHESIZED GENE FOR A MINI-C ANALOG OF HUMAN PROINSULIN [J].

WETZEL, R ;

KLEID, DG ;

CREA, R ;

HEYNEKER, HL ;

YANSURA, DG ;

HIROSE, T ;

KRASZEWSKI, A ;

RIGGS, AD ;

ITAKURA, K ;

GOEDDEL, DV .

GENE, 1981, 16 (1-3) :63-71

[38]

WETZEL R, 1983, PEPTIDES ANAL SYNTHE, V5, P1

[39]

WETZEL R, 1983, BIOL INTERFERON SYST, P101

[40] SITE-DIRECTED MUTAGENESIS AS A PROBE OF ENZYME STRUCTURE AND CATALYSIS - TYROSYL-TRANSFER RNA-SYNTHETASE CYSTEINE-35 TO GLYCINE-35 MUTATION [J].

WILKINSON, AJ ;

FERSHT, AR ;

BLOW, DM ;

WINTER, G .

BIOCHEMISTRY, 1983, 22 (15) :3581-3586

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