CHARACTERIZATION OF AN ANTITHROMBOTIC PEPTIDE FROM KAPPA-CASEIN IN NEWBORN PLASMA AFTER MILK INGESTION

被引：108

作者：

CHABANCE, B

JOLLES, P

IZQUIERDO, C

MAZOYER, E

FRANCOUAL, C

DROUET, L

FIAT, AM

机构：

[1] HOP LARIBOISIERE, INST VAISSEAUX & SANG, F-75010 PARIS, FRANCE

[2] HOP ST VINCENT DE PAUL, F-75674 PARIS 14, FRANCE

来源：

BRITISH JOURNAL OF NUTRITION | 1995年 / 73卷 / 04期

关键词：

CASEIN; ANTITHROMBOTIC PEPTIDES; NEWBORN INFANTS;

D O I：

10.1079/BJN19950060

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Bovine and human kappa-caseinoglycopeptides, two antithrombotic peptides derived from the corresponding kappa-caseins, were detected in physiologically active concentrations in the plasma of 5-d-old newborn infants after ingestion of cow's-milk-based formula or human milk respectively. It is suggested that these two bioactive peptides are released from milk proteins during digestion.

引用

收藏

页码：583 / 590

页数：8

相关论文

共 14 条

[1] RELATION OF INFANT-FEEDING TO ADULT SERUM-CHOLESTEROL CONCENTRATION AND DEATH FROM ISCHEMIC-HEART-DISEASE [J].

FALL, CHD ;

BARKER, DJP ;

OSMOND, C ;

WINTER, PD ;

CLARK, PMS ;

HALES, CN .

BRITISH MEDICAL JOURNAL, 1992, 304 (6830) :801-805

[2] BIOLOGICALLY-ACTIVE PEPTIDES FROM MILK-PROTEINS WITH EMPHASIS ON 2 EXAMPLES CONCERNING ANTITHROMBOTIC AND IMMUNOMODULATING ACTIVITIES [J].

FIAT, AM ;

MIGLIORESAMOUR, D ;

JOLLES, P ;

DROUET, L ;

SOLLIER, CBD ;

CAEN, J .

JOURNAL OF DAIRY SCIENCE, 1993, 76 (01) :301-310

[3] GASTROINTESTINAL ABSORPTION OF INTACT PROTEINS [J].

GARDNER, MLG .

ANNUAL REVIEW OF NUTRITION, 1988, 8 :329-350

[4]

JOLLES P, 1986, EUR J BIOCHEM, V158, P379, DOI 10.1111/j.1432-1033.1986.tb09764.x

[5] ETUDE COMPAREE DES CASEINO-GLYCOPEPTIDES FORMES PAR ACTION DE LA PRESURE SUR LES CASEINES DE VACHE, DE BREBIS ET DE CHEVRE .1. ETUDE DE LA PARTIE PEPTIDIQUE [J].

JOLLES, P ;

JOLLES, J ;

ALAIS, C .

BIOCHIMICA ET BIOPHYSICA ACTA, 1961, 51 (02) :309-&

[6] SOME ASPECTS OF GASTRIF FUNCTION IN NEWBORN [J].

MASON, S .

ARCHIVES OF DISEASE IN CHILDHOOD, 1962, 37 (194) :387-+

[7] AN IMPROVED METHOD FOR ISOLATIN OF KAPPA-CASEIN [J].

MCKENZIE, HA ;

WAKE, RG .

BIOCHIMICA ET BIOPHYSICA ACTA, 1961, 47 (02) :240-&

[8] CHEMICAL CHARACTERIZATION OF BIOACTIVE PEPTIDES FROM INVIVO DIGESTS OF CASEIN [J].

MEISEL, H ;

FRISTER, H .

JOURNAL OF DAIRY RESEARCH, 1989, 56 (03) :343-349

[9] FURTHER EVIDENCE FOR FORMATION INVIVO OF PHOSPHOPEPTIDE IN INTESTINAL LUMEN FROM DIETARY BETA-CASEIN [J].

NAITO, H ;

SUZUKI, H .

AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1974, 38 (AUG) :1543-1545

[10] FORMATION OF A PEPTIDE INHIBITOR OF GASTRIC-SECRETION FROM RAT MILK-PROTEINS INVIVO [J].

STAN, EY ;

CHERNIKOV, MP .

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 1982, 94 (08) :1087-1089