SYNTHESIS OF A NOVEL SPIROCYCLIC LACTONE IN A POTENTIAL ROUTE TO SQUALESTATIN-1

被引：13

作者：

ABDELRAHMAN, H

ADAMS, JP

BOYES, AL

KELLY, MJ

LAMONT, RB

MANSFIELD, DJ

PROCOPIOU, PA

ROBERTS, SM

SLEE, DH

WATSON, NS

机构：

[1] GLAXO RES & DEV LTD,DEPT STRUCT CHEM,GREENFORD UB6 0HE,MIDDX,ENGLAND

[2] GLAXO RES & DEV LTD,DEPT MED CHEM 1,GREENFORD UB6 0HE,MIDDX,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1994年 / 10期

关键词：

D O I：

10.1039/p19940001259

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The isomeric butenolides 1 and 2 have been converted into the spiro-lactone derivative 20 via sequential ring contraction-rearrangement processes. X-Ray crystal data have been obtained on compound 12b.

引用

页码：1259 / 1261

页数：3

共 14 条

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