CROSSTALK IN THE MOUSE THYMUS

被引：219

作者：

VANEWIJK, W ^{[1
]}

SHORES, EW ^{[1
]}

SINGER, A ^{[1
]}

机构：

[1] NCI,EXPTL IMMUNOL BRANCH,BETHESDA,MD 20892

来源：

IMMUNOLOGY TODAY | 1994年 / 15卷 / 05期

关键词：

D O I：

10.1016/0167-5699(94)90246-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The development of mature T cells within the thymus is dependent upon intact cortical and medullary microenvironments. In turn, thymic microenvironments themselves are dependent on lymphoid cells to maintain their integrity. Here, Willem van Ewijk and colleagues discuss experiments that have established the phenomenon of 'crosstalk' within the mouse thymus and suggest a mechanism whereby lymphoid and stromal cells influence each other in a consecutive manner during T-cell development.

引用

页码：214 / 217

页数：4

共 33 条

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