BIOTRANSFORMATION OF UNSATURATED HETEROCYCLIC RINGS BY PSEUDOMONAS-PUTIDA TO YIELD CIS-DIOLS

被引：47

作者：

BOYD, DR

SHARMA, ND

BOYLE, R

MCMURRAY, BT

EVANS, TA

MALONE, JF

DALTON, H

CHIMA, J

SHELDRAKE, GN

机构：

[1] UNIV WARWICK,DEPT BIOL SCI,COVENTRY CV4 7AL,W MIDLANDS,ENGLAND

[2] ICI FINE CHEM MFG ORG,HUDDERSFIELD HD2 1FF,YORKS,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1993年 / 01期

关键词：

D O I：

10.1039/c39930000049

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New cis-diol metabolites of both aromatic and non-aromatic heterocyclic rings have been isolated from growing cultures of a mutant strain of the soil bacterium Pseudomonas putida (UV4) and stereochemically assigned; a novel heterocyclic cis-diol of benzothiophene, 2,3-dihydroxy-2,3-dihydrobenzothiophene is found to exist exclusively in the cis-configuration in water but equilibrates readily with the trans-isomer.

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页码：49 / 51

页数：3

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