ICE-LIKE PROTEASES IN APOPTOSIS

被引：367

作者：

KUMAR, S

机构：

[1] S. Kumar is at the Hanson Centre for Cancer Research, Post Office, Adelaide, SA 5000, Rundle Mall

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1995年 / 20卷 / 05期

关键词：

D O I：

10.1016/S0968-0004(00)89007-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The discovery of structural and functional similarities between the product of the nematode cell-death gene ced-3 and mammalian interleukin-1 beta-converting enzyme (ICE) is providing important insights into the molecular mechanism of apoptosis. This article summarizes the current knowledge of ICE and its homologues, and how these may be involved in regulating apoptosis.

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页码：198 / 202

页数：5

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