INVITRO METABOLISM OF SPARTEINE BY HUMAN-LIVER - COMPETITIVE-INHIBITION BY DEBRISOQUINE

被引：57

作者：

OTTON, SV ^{[1
]}

INABA, T ^{[1
]}

MAHON, WA ^{[1
]}

KALOW, W ^{[1
]}

机构：

[1] UNIV TORONTO,FAC MED,DEPT PHARMACOL,TORONTO M5S 1A8,ONTARIO,CANADA

来源：

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY | 1982年 / 60卷 / 01期

关键词：

D O I：

10.1139/y82-017

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：102 / 105

页数：4

共 11 条

[1] PHARMACOGENETIC COVARIATION OF DEFECTIVE N-OXIDATION OF SPARTEINE AND 4-HYDROXYLATION OF DEBRISOQUINE
BERTILSSON, L
DENGLER, HJ
EICHELBAUM, M
SCHULZ, HU
[J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1980, 17 (02) : 153 - 155
[2] NORTRIPTYLINE AND ANTIPYRINE CLEARANCE IN RELATION TO DEBRISOQUINE HYDROXYLATION IN MAN
BERTILSSON, L
EICHELBAUM, M
MELLSTROM, B
SAWE, J
SCHULZ, HU
SJOQVIST, F
[J]. LIFE SCIENCES, 1980, 27 (18) : 1673 - 1677
[3] EVIDENCE FOR AN ENZYMATIC DEFECT IN THE 4-HYDROXYLATION OF DEBRISOQUINE BY HUMAN-LIVER
DAVIES, DS
KAHN, GC
MURRAY, S
BRODIE, MJ
BOOBIS, AR
[J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1981, 11 (01) : 89 - 91
[4] DEFECTIVE N-OXIDATION OF SPARTEINE IN MAN - NEW PHARMACOGENETIC DEFECT
EICHELBAUM, M
SPANNBRUCKER, N
STEINCKE, B
DENGLER, HJ
[J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1979, 16 (03) : 183 - 187
[5] A FAMILY AND POPULATION STUDY OF THE GENETIC-POLYMORPHISM OF DEBRISOQUINE OXIDATION IN A WHITE BRITISH-POPULATION
EVANS, DAP
MAHGOUB, A
SLOAN, TP
IDLE, JR
SMITH, RL
[J]. JOURNAL OF MEDICAL GENETICS, 1980, 17 (02) : 102 - 105
[6] POLYMORPHISMS OF OXIDATION AT CARBON CENTERS OF DRUGS AND THEIR CLINICAL SIGNIFICANCE
IDLE, JR
SMITH, RL
[J]. DRUG METABOLISM REVIEWS, 1979, 9 (02) : 301 - 317
[7] DEFICIENT METABOLISM OF DEBRISOQUINE AND SPARTEINE
INABA, T
OTTON, SV
KALOW, W
[J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 1980, 27 (04) : 547 - 549
[8] POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN
MAHGOUB, A
IDLE, JR
DRING, LG
LANCASTER, R
SMITH, RL
[J]. LANCET, 1977, 2 (8038) : 584 - 586
[9] POLYMORPHISM OF CARBON OXIDATION OF DRUGS AND CLINICAL IMPLICATIONS
SLOAN, TP
MAHGOUB, A
LANCASTER, R
IDLE, JR
SMITH, RL
[J]. BRITISH MEDICAL JOURNAL, 1978, 2 (6138) : 655 - 657
[10] TUCKER GT, 1977, LANCET, V2, P718

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