SYNTHESIS OF STEREOCHEMICALLY HOMOGENEOUS OLIGORIBONUCLEOSIDE ALL-R(P)-PHOSPHOROTHIOATES BY COMBINING H-PHOSPHONATE CHEMISTRY AND ENZYMATIC DIGESTION

被引：18

作者：

ALMER, H ^{[1
]}

STAWINSKI, J ^{[1
]}

STROMBERG, R ^{[1
]}

机构：

[1] STOCKHOLM UNIV,DEPT ORGAN CHEM,ARRHENIUS LAB,S-10691 STOCKHOLM,SWEDEN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 12期

关键词：

D O I：

10.1039/c39940001459

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Oligouridine all-R(p)-phosphorothioates were synthesized using the H-phosphonate approach followed by sulfurisation with S-8 and treatment with nuclease P1.

引用

页码：1459 / 1460

页数：2

共 12 条

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