A POSITION EFFECT ON THE EXPRESSION OF A TRANSFER-RNA GENE MEDIATED BY THE SIR GENES IN SACCHAROMYCES-CEREVISIAE

被引：97

作者：

SCHNELL, R ^{[1
]}

RINE, J ^{[1
]}

机构：

[1] UNIV CALIF BERKELEY, DEPT BIOCHEM, BERKELEY, CA 94720 USA

来源：

MOLECULAR AND CELLULAR BIOLOGY | 1986年 / 6卷 / 02期

关键词：

D O I：

10.1128/MCB.6.2.494

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The SIR genes of Saccharomyces cerevisiae are responsible for the position-dependent regulation of the a and .alpha. mating-type genes. Previous work by others has shown that the products of the SIR genes prevent the accumulation of stable transcripts of the a and .alpha. genes at HML and HMR. Results of this study establish that this regulation is a region-specific effect rather than a gene-specific effect since expression of a tRNA gene placed at HMR is repressed by the products of the SIR genes.

引用

页码：494 / 501

页数：8

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