ABSENCE OF HEPATIC CYTOCHROME P450BUFI CAUSES GENETICALLY DEFICIENT DEBRISOQUINE OXIDATION IN MAN

被引：179

作者：

ZANGER, UM

VILBOIS, F

HARDWICK, JP

MEYER, UA

机构：

[1] UNIV BASEL,BIOCTR,DEPT PHARMACOL,CH-4056 BASEL,SWITZERLAND

[2] ARGONNE NATL LAB,DIV BIOMED,ARGONNE,IL 60439

来源：

关键词：

D O I：

10.1021/bi00415a010

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：5447 / 5454

页数：8

共 36 条

[21] LOWRY OH, 1951, J BIOL CHEM, V193, P265
[22] McIntosh J E, 1980, Monogr Endocrinol, V16, P1
[23] MEIER PJ, 1983, GASTROENTEROLOGY, V85, P682
[24] THE MOLECULAR MECHANISMS OF 2 COMMON POLYMORPHISMS OF DRUG OXIDATION - EVIDENCE FOR FUNCTIONAL-CHANGES IN CYTOCHROME-P-450 ISOZYMES CATALYZING BUFURALOL AND MEPHENYTOIN OXIDATION
MEYER, UA
GUT, J
KRONBACH, T
SKODA, C
MEIER, UT
CATIN, T
DAYER, P
[J]. XENOBIOTICA, 1986, 16 (05) : 449 - 464
[25] MEYER UA, 1984, 2ND P WORLD C CLIN P, P331
[26] BUFURALOL METABOLISM IN HUMAN-LIVER - A SENSITIVE PROBE FOR THE DEBRISOQUINE-TYPE POLYMORPHISM OF DRUG OXIDATION
MINDER, EI
MEIER, PJ
MULLER, HK
MINDER, C
MEYER, UA
[J]. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 1984, 14 (03) : 184 - 189
[27] THE P450 GENE SUPERFAMILY - RECOMMENDED NOMENCLATURE
NEBERT, DW
ADESNIK, M
COON, MJ
ESTABROOK, RW
GONZALEZ, FJ
GUENGERICH, FP
GUNSALUS, IC
JOHNSON, EF
KEMPER, B
LEVIN, W
PHILLIPS, IR
SATO, R
WATERMAN, MR
[J]. DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY, 1987, 6 (01): : 1 - 11
[28] OMURA T, 1964, J BIOL CHEM, V239, P2370
[29] COMPETITIVE-INHIBITION OF SPARTEINE OXIDATION IN HUMAN-LIVER BY BETA-ADRENOCEPTOR ANTAGONISTS AND OTHER CARDIOVASCULAR DRUGS
OTTON, SV
INABA, T
KALOW, W
[J]. LIFE SCIENCES, 1984, 34 (01) : 73 - 80
[30] PRICEEVANS DA, 1980, J MED GENET, V17, P102