TOXIN INACTIVATION AND ANTIGEN STABILIZATION - 2 DIFFERENT USES OF FORMALDEHYDE

被引：48

作者：

RAPPUOLI, R

机构：

来源：

VACCINE | 1994年 / 12卷 / 07期

关键词：

FORMALDEHYDE; DETOXIFICATION; ANTIGEN STABILITY;

D O I：

10.1016/0264-410X(94)90259-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Since the 1920s, when Ramon discovered the detoxifying properties of formaldehyde, this compound has been used to inactivate toxins, whole bacterial cells and viruses. With the development of vaccines that are detoxified by genetic manipulation, formaldehyde has a new role as a stabilizer of such genetically detoxified antigens.

引用

页码：579 / 581

页数：3

共 14 条

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