UNDERFEEDING AND BODY-WEIGHT REGULATION IN NORMAL-WEIGHT YOUNG MEN

被引:51
作者
HEYMAN, MB
YOUNG, VR
FUSS, P
TSAY, R
JOSEPH, L
ROBERTS, SB
机构
[1] MIT, HUMAN NUTR LAB, E17-613, 40 AMES ST, CAMBRIDGE, MA 02139 USA
[2] TUFTS UNIV, USDA, HUMAN NUTR RES CTR AGING, BOSTON, MA 02111 USA
[3] SHRINERS BURN INST, BOSTON, MA 02139 USA
来源
AMERICAN JOURNAL OF PHYSIOLOGY | 1992年 / 263卷 / 02期
关键词
DOUBLY LABELED WATER; FAT; OBESITY; ENERGY METABOLISM; BODY COMPOSITION;
D O I
10.1152/ajpregu.1992.263.2.R250
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
The mechanisms of energy regulation invoked by moderate dietary restriction were investigated in seven healthy young men of normal body weight leading unrestricted lives. Following a baseline period of weight maintenance, subjects were underfed by 806 +/- 162 (mean +/- SE) kcal/day for 21 days. Changes in total energy expenditure (TEE) and resting energy expenditure (REE) and subsequent voluntary nutrient intakes were measured. The REE, averaged for fasting and fed states, decreased during underfeeding by 100 +/- 29 kcal/day (P < 0.01). TEE decreased nonsignificantly by 296 +/- 170 kcal/day, equivalent to an average of 37% of the decrease in energy intake. Body energy stores were estimated to decrease by 510 +/- 172 kcal/day (P < 0.03), thus compensating for 63% of the dietary energy deficit on average. Voluntary energy intake following dietary restriction increased above the initial amount required for body weight maintenance, was proportional to the weight loss during underfeeding (P < 0.03), and was associated with a rapid repin of weight lost during underfeeding. These results indicate that energy balance is regulated by adaptive variations in both energy intake and energy expenditure in normal-weight young men leading unrestricted lives but do not support the hypothesis that energy-wasting mechanisms contribute substantially to body energy regulation.
引用
收藏
页码:R250 / R257
页数:8
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