THE USE OF ADENOVIRAL VECTORS FOR GENE-THERAPY AND GENE-TRANSFER IN-VIVO

被引：90

作者：

BRAMSON, JL

GRAHAM, FL

GAULDIE, J

机构：

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 1995年 / 6卷 / 05期

关键词：

D O I：

10.1016/0958-1669(95)80097-2

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Adenoviral vectors have proven to be excellent vehicles for gene delivery in vivo to a wide range of cell types. These vectors have been used to transfer genes such as CFTR to correct the defect in cystic fibrosis and, more recently, to supply serum blood factors and genetically modify tumors to enhance therapy.

引用

页码：590 / 595

页数：6

共 49 条

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