COEXISTENCE OF PAIRED HELICAL FILAMENTS AND GLIAL FILAMENTS IN ASTROCYTIC PROCESSES WITHIN GHOST TANGLES

被引：29

作者：

IKEDA, K ^{[1
]}

HAGA, C ^{[1
]}

AKIYAMA, H ^{[1
]}

KASE, K ^{[1
]}

IRITANI, S ^{[1
]}

机构：

[1] TOKYO METROPOLITAN MATSUZAWA HOSP,TOKYO,JAPAN

来源：

NEUROSCIENCE LETTERS | 1992年 / 148卷 / 1-2期

关键词：

ALZHEIMERS DISEASE; ASTROCYTE; GHOST TANGLE; PAIRED HELICAL FILAMENT;

D O I：

10.1016/0304-3940(92)90820-W

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Ultrastructural examination of ghost tangles in an autopsy case of long-term Alzheimer's disease revealed, in addition to degenerate neurites containing paired helical filaments (PHF), astrocytic processes which included PHF. This finding suggests either that astrocytes in ghost tangles possess the capacity to produce PHF or that PHF are incorporated into astrocytes by endocytosis.

引用

页码：126 / 128

页数：3

共 10 条

[1]

AMANO N, COMMUNICATION

[2] MICROGLIA ARE ASSOCIATED WITH THE EXTRACELLULAR NEUROFIBRILLARY TANGLES OF ALZHEIMER-DISEASE [J].