9,11-EPOXY-9-HOMO-14-THIAPROST-5-ENOIC ACID-DERIVATIVES - POTENT THROMBOXANE-A2 ANTAGONISTS

被引：20

作者：

HALL, SE ^{[1
]}

HAN, WC ^{[1
]}

HARRIS, DN ^{[1
]}

HEDBERG, A ^{[1
]}

OGLETREE, ML ^{[1
]}

机构：

[1] SQUIBB INST MED RES,DEPT PHARMACOL,PRINCETON,NJ 08540

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 05期

关键词：

D O I：

10.1021/jm00125a009

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：974 / 984

页数：11

共 59 条

[31]

HENDRA T, 1983, LANCET, P1041

[32] HIGHLY SELECTIVE INHIBITORS OF THROMBOXANE SYNTHETASE .1. IMIDAZOLE DERIVATIVES [J].

IIZUKA, K ;

AKAHANE, K ;

MOMOSE, DI ;

NAKAZAWA, M ;

TANOUCHI, T ;

KAWAMURA, M ;

OHYAMA, I ;

KAJIWARA, I ;

IGUCHI, Y ;

OKADA, T ;

TANIGUCHI, K ;

MIYAMOTO, T ;

HAYASHI, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (10) :1139-1148

[33] SYNTHESIS AND BIOLOGICAL EVALUATION OF 9,11-AZO-13-OXA-15-HYDROXYPROSTANOIC ACID, A POTENT INHIBITOR OF PLATELET-AGGREGATION [J].

KAM, ST ;

PORTOGHESE, PS ;

GERRARD, JM ;

DUNHAM, EW .

JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (11) :1402-1408

[34]

KIFF PS, 1983, BR J CLIN PHARM, V15, P783

[35]

LEBRETON GC, 1979, P NATL ACAD SCI USA, V76, P4097

[36] DAZOXIBEN, A THROMBOXANE SYNTHETASE INHIBITOR, IN RAYNAUDS-PHENOMENON [J].

LUDERER, JR ;

NICHOLAS, GG ;

NEUMYER, MM ;

RILEY, DL ;

VARY, JE ;

GARCIA, G ;

SCHNECK, DW .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1984, 36 (01) :105-115

[37] STRUCTURE-ACTIVITY-RELATIONSHIPS IN AN IMIDAZOLE-BASED SERIES OF THROMBOXANE SYNTHASE INHIBITORS [J].

MANLEY, PW ;

ALLANSON, NM ;

BOOTH, RFG ;

BUCKLE, PE ;

KUZNIAR, EJ ;

LAD, N ;

LAI, SMF ;

LUNT, DO ;

TUFFIN, DP .

JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (09) :1588-1595

[38]

MAXEY KM, 1980, TETRAHEDRON LETT, P445

[39]

MCGIBNEY D, 1983, CLIN SCI, P12

[40] SIMPLE SYNTHESIS OF METHYL (5Z,9-ALPHA,11-ALPHA,13E,15S)-9,11-EPIDITHIO-15-HYDROXYPROSTA-5,13-DIENOATE,ENDODISULFIDE ANALOG OF PGH2 [J].

MIYAKE, H ;

IGUCHI, S ;

ITOH, H ;

HAYASHI, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1977, 99 (10) :3536-3537

← 1 2 3 4 5 6 →